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Mothering From the Heart
A Professional Breastfeeding Consultation Service
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Risks of
Artificial Feeding
(Studies done mostly in affluent societies) Risks to infant and child Review: 1. Walker M. A fresh look at the risks of artificial
feeding. J Hum Lact 1993;9:97-107 2. Cunningham AS, Jelliffe DB, Jelliffe EFP.
Breastfeeding and health in the 1980’s: a global epidemiologic review. J
Pediatr 1991;118:659-66 Cognitive Development: CD (review): Andraca I, Uauy R. Breastfeeding for
optimal mental development. Simopoulos AP, Dutra de Oliveira JE, Desai ID
(eds): Behavioral and Metabolic Aspects of Breastfeeding. World Rev
Nutr Diet. Basel, Karger, 1995;78:1-27 CD (review): Gordon N. Nutrition and cognitive
function. Brain and Development 1997;19:165-70 CD-1: Morrow-Tlucak M, Haude RH, Ernhart CB.
Breastfeeding and cognitive development in the first 2 years of life. Soc
Sci Med 1988;26:635-9 CD-2: Taylor B, Wadsworth J. Breastfeeding and child
development at five years. Dev Med Child Neurol 1984;26:73-80 CD-3: Lucas A, Morley R, Cole TJ, Lister G, Leeson-Payne
C. Breastmilk and subsequent intelligence quotient in children born
preterm. Lancet 1992;339:261-4 CD-4: Nettleton JA. Are n-3 fatty acids essential
nutrients for fetal and infant development. J Am Diet Assoc 1993;93:58-64 CD-5: Rogan WJ, Gladen BC. Breastfeeding and cognitive
development. Early Hum Dev 1993;31:181-93 CD-6: Silver LB, Levinson RB, Laskin CR, Pilot LJ.
Learning disabilities as a probable consequence of using
chloride-deficient infant formula. J Pediatr 1989;115:97-9 CD-7: Willoughby A, Moss HA, Hubbard VS, Bercu BB,
Graubard BI, Vietze PM, et al. Developmental outcome in children
exposed to chloride deficient formula. Pediatrics 1987;79:851-7 CD-8: Wing CS. Defective infant formulas and expressive
language problems: a case study. Language, Speech and Hearing Services
in Schools 1990;21:22-7 CD-9: Crawford MA. The role of essential fatty acids in
neural development: implications for perinatal nutrition. Am J Clin
Nutr 1993;57(suppl):703S-10S CD-10: Temboury MC, Otero A, Polanco I, Arribas E.
Influence of breastfeeding on the infant’s intellectual development. J
Pediatric Gastroenterol Nutr 1994;18:32-36 CD-11: Pollock JI. Longterm associations with infant
feeding in a clinically advantaged population of babies. Dev Med Child
Neur 1994;36:429-40 CD-12: Makrides M, Neumann MA, Byard RW, Simmer K,
Gibson RA. Fatty acid composition of brain, retina and erythrocytes in
breast and formula fed infants. Am J Clin Nutr 1994;60:189-94 CD-14: Anderson GJ, Connor WE, Corliss JD.
Docosohexaenoic acid is the preferred dietary n-3 fatty acid for the
development of the brain and retina. Pediatr Res 1990;27:87-97 CD-15: Neuringer M, Connor WE, Lin DS, Barstad L, Luck
S. Biochemical and functional effects of prenatal and postnatal fatty acid
deficiency on retina and brain in rhesus monkeys. Proc Natl Acad Sc USA
1986;83:4021-5 CD-16: Florey C Du V, Leech AM, Blackhall A. Infant
feeding and mental and motor development at 18 months of age in first born
singletons. Int J Epidem 1995;24 (Suppl 1):S21-6 CD-17: Wang YS, Wu SY. The effect of exclusive
breastfeeding on development and incidence of infection in infants. JHL
1996;12:27-30 CD-18: Greene LC, Lucas A, Livingstone BE, Harland PSEG,
Baker BA. Relationship between early diet and subsequent cognitive
performance during adolescence. Biochem Soc Trans 1995;23:376S CD-19: Riva E, Agostoni C, Biasucci G, Trojan S, Luotti
D, Fiori L, et al. Early breastfeeding is linked to higher
intelligence quotient scores in dietary treated phenylketonuric children. Acta
Pædiatr 1996;85:56-8 CD-20: Niemelä A, Järvenpää A-L. Is breastfeeding
beneficial and maternal smoking harmful to the cognitive development of
children? Acta Pædiatr 1996;85:1202-6 CD-21: Rodgers B. Feeding in infancy and later ability
and attainment: a longitudinal study. Devel Med Child Neurol 1978;20:421-6 CD-22: Horwood LJ, Fergusson DM. Breastfeeding and
later cognitive and academic outcomes. Pediatrics 1998;101:p. e9 CD-23: Paine BJ, Makrides M, Gibson RA. Duration of
breastfeeding and Bayley's mental developmental Index at 1 year of age. J
Paediatr Child Health 1999;35:82-5 CD-24: Fergusson DM, Beautrais AL, Silva PA.
Breastfeeding and cognitive development In the first seven years of life. Soc
Sci Med 1982;16:1705-8 CD-25: Vestergaard M, Obel C, Henriksen TB, Sørensen
HT, Skajaa E, Østergaard J. Duration of breastfeeding and developmental
milestones during the latter half of Infancy. Acta Paediatr 1999;88:1327-32 Neurologic Outcome N-1: Lanting CI, Fidler V, Huisman M, Touwen BCL,
Boersma ER. Neurological differences between 9 year old children fed
breastmilk or formula milk as babies. Lancet 1994;344:1319-22 N-2: Lanting CI, Patandin S, Weisglas-Kuperus N, Touwen
BCL, Boersma ER.Breastfeeding and neurological outcome at 42 months. Acta
Paediatr 1998;87:1224-9 SIDS: SIDS-1: Mitchell EA, Scragg R, Stewart AW, Becroft DMO,
Taylor BJ, For RPK, et al. Results from the first year of the New
Zealand cot death study. NZ Med J 1991;104:71-6 Insulin Dependent Diabetes: Working Group on Cow’s Milk Protein and Diabetes
Mellitus of the American Academy of Pediatrics. Infant feeding practices
and their possible relationship to the etiology of diabetes mellitus. Pediatrics
1994;94:752-4 JD-1: Karjalainen J, Martin JM, Knip M, Ilonen J,
Robinson BH, Savilahti E, et al. A bovine albumin peptide as a
possible trigger of insulin-dependent diabetes mellitus. N Eng J Med 1992;327:302-7
(Editorial: 1992:327:348-9) JD-2: Mayer EJ, Hamman RF, Gay EC, Lezotte DC, Savitz
DA, Klingensmith J. Reduced risk of IDDM among breastfed children. Diabetes
1988;37:1625-32 JD-3: Virtanen SM, Räsänen L, Ylönen K, Aro A,
Clayton D, Langlholz B, et al. Early introduction of dairy products
associated with increased risk of IDDM in Finnish children. Diabetes 1993;42:1786-90 JD-4: Virtanen SM, Räsänen L, Aro A, Lindström J,
Sippola H, Lounamaa R, et al. Infant feeding in Finnish children
<7 yr of age with newly diagnosed IDDM. Diabetes Care 1991;14:415-17 JD-5: Gerstein HC. Cow’s milk exposure and type I
diabetes mellitus. Diabetes Care 1994;17:13-9 JD-6: Kostraba JN, Cruickshanks KJ, Lawler-Heavner J,
Jobim LF, Rewers MJ, Gay EC, et al. Early exposure to cow’s milk and
solid foods in infancy, genetic predisposition, and risk of IDDM. Diabetes
1993;42:288-95 JD-7: Pérez-Bravo F, Carrasco E, Gutierrez-López MD,
Martínez MT, López G, García de los Rios M. Genetic predisposition and
environmental factors leading to the development of insulin-dependent
diabetes mellitus in Chilean children. J Mol Med 1996;74:105-9 JD-8: Gimeno SGA, De Souza JMP. IDDM and milk
consumption. Diabetes Care 1997;20:1256-60 JD-9: Hammond-McKibbon D, Karges W, Gaedigk R, Dosch
H-M. Immunological mechanisms that link cow milk protein and insulin
dependent diabetes: a synopsis. Can J Allergy and Clin Immunol 1997;2:136-46 Cow milk Allergy and Intolerance: CM-1: Høst A. Importance of the first meal on the
development of cow’s milk allergy and intolerance. Allergy Proc 1991;12:227-32 Respiratory Illness: RI-1: Pullan CR, Toms GL, Martin AJ, Gardner PS, Webb
JKG, Appleton DR. Breastfeeding and respiratory syncytial virus infection.
Br Med J 1980;281:1034-6 RI-2: Chiba Y, Minagawa T, Mito K, Nakane A, Suga K,
Honjo T, Nakao T. Effect of breastfeeding on responses of systemic
interferon and virus-specific lymphocyte transformation with respiratory
syncytial virus infection. J Med Virology 1987;21:7-14 RI-3: Wright AL, Holberg CJ, Martinez FD, Morgan WJ,
Taussig LM. Breastfeeding and lower respiratory tract illness in the first
year of life. Br Med J 1989;299:946-9 RI-4: Porro E, Indinnimeo L, Antognoni G, Midulla F,
Criscione S. Early wheezing and breastfeeding. J Asthma 1993;30:23-8 RI-5: Burr ML, Limb ES, Maguire JM, Amarah L, Eldridge
BA, Layzell JCM, Merret TG. Infant feeding, wheezing, and allergy: a
prospective study. Arch Dis Child 1993;68:724-28 RI-6: Pisacane A, Graziano L, Zona G, Granata G,
Dolezalova H, Cafiero M, et al. Breastfeeding and acute lower
respiratory infection. Acta Pædiatr 1994;83:714-18 RI-7: Beaudry M, Dufour R, Marcoux S. Relation between
infant feeding and infections during the first six months of life. J
Pediatr 1995;126:191-7 RI-8: Okamoto Y, Ogra PL. Antiviral factors in human
milk: implications in respiratory syncytial virus infection. Acta
Pædiatr Scand Suppl 1989;351:137-43 RI-9: Downham MAPS, Scott R, Sims DG, Webb JKG, Gardner
PS. Breastfeeding protects against respiratory syncytial virus infections.
Br Med J 1976;2:274-6 RI-10: Wright AL, Holberg CJ, Taussig LM, Martinez FD.
Relationship of infant feeding to recurrent wheezing at age 6 years. Arch
Pediatr Adolesc Med 1995;149:758-63 RI-11: Yue Chen. Synergistic effect of passive smoking
and artificial feeding on hospitalization for respiratory illness in early
childhood. Chest 1989;95:1004-07 RI-12: Wilson AC, Forsyth JS, Greene SA, Irvine L, Hau
C, Howie PW. Relation of infant diet to childhood health: seven year
followup of cohort of children in Dundee infant feeding study. Br Med J
1998;316:21-5 (also shows higher blood pressure in formula fed
children) RI-13: Oddy WH, Holt PG, Sly PD, Read AW, Landau LI,
Stanley FJ, Kendall GE, Burton PR. Association between breastfeeding and
asthma in 6 year old children: findings of a prospective birth cohort
study. Br Med J 1999;319:815-9 RI-14: César JA, Victora CG, Barros FC, Santos IS,
Flores JA. Impact of breastfeeding on admission for pneumonia during
postneonatal period in Brazil: nested case-control study. Br Med J 1999;318:1316-20 RI-15: Pisacane A, Impagliazzo N, De Caprio C,
Criscuolo L, Inglese A, da Silva MCMP. Breastfeeding and tonsillectomy. Br
Med J 1996;?:? RI-16: López-Alarcón M, Villalpando S, Fajardo A.
Breastfeeding lowers the frequency and duration of acute respiratory
infection and diarrhea in infants under 6 months of age. J Nutr 1997;127:436-43 Otitis Media: OM-1: Saarinen UM. Prolonged breastfeeding as
prophylaxis for recurrent otitis media. Acta Pediatr Scand 1982;71:567-71 OM-2: Teele DW, Klein JO, Rosner B. Epidemiology of
otitis media during the first seven years of life in children in greater
Boston: a prospective cohort study. J Infect Dis 1989;160:83-94 OM-3: Duncan B, Ey J, Holberg CJ, Wright AL, Martinez
FD, Taussig LJ. Exclusive breastfeeding for at least 4 months protects
against otitis media. Pediatrics 1993;91:867-72 OM-4: Owen MJ, Baldwin CD, Swank PR, Pannu AK, Johnson
DL, Howie VM. Relation of infant feeding practices, cigarette smoke
exposure and group child care to the onset and duration of otitis media
with effusion in the first two years of life. J Pediatr 1993;123:702-11 OM-5: Harabuchi Y, Faden H, Yamanaka N, Duffy L, Wolf
J, Krystofik D. Human milk secretory IgA antibody to nontypeable Hæmophilus
influenzæ: Possible protective effects against nasopharyngeal
colonization. J Pediatr 1994;124:193-8 OM-6: Aniansson G, Alm B, Andersson B, Håkansson A,
Larsson P, Nylén O, et al. A prospective cohort study on
breastfeeding and otitis media in Swedish infants. Pediatr Infect Dis J
1994;13:183-8 OM-7: Paradise JL, Elster BA, Tan L. Evidence in
infants with cleft palate that breast milk protects against otitis media. Pediatrics
1994;94:853-60 OM-8: Sassen ML, Brand R, Grote JJ. Breastfeeding and
acute otitis media. Am J Otolaryn 1994;15:351-7 OM-9: Dewey KG, Heinig J, Nommsen-Rivers LA.
Differences in morbidity between breastfed and formula fed infants. J
Pediatr 1995;126:696-702 (risk also increased in FF infant for
diarrhea) OM-10: Scariati PD, Grummer-Strawn LM, Fein SB. A
longitudinal analysis of infant morbidity and the extent of breastfeeding
in the United States. Pediatrics 1997;99:e5 Risks for the premature baby: P-1: Lucas A, Cole TJ. Breastmilk and neonatal
necrotizing enterocolitis. Lancet 1990;336:1519-23 P-2: El-Mohandes AE, Picard MB, Simmens SJ, Keiser JF.
Use of human milk in the intesive care nursery decreases the incidence of nosocomial
sepsis. J Perinatol 1997;17:130-4 P-3: Daniels L, Gibson R, Simmer K. Selenium status of
preterm infants: the effect of postnatal age and method of feeding. Acta
Pædiatr 1997;86:281-8 (M:23) P-4: Uauy RD, Birch DG, Birch EE, Tyson JE, Hoffman DR.
Effect of dietary omega-3 fatty acids on retinal function of very
low birth weight neonates. Pediatr Res 1990;28:485-92 (M:18) P-5: Lucas A, Morley R, Cole TJ, Lister G, Leeson-Payne
C. Breastmilk and subsequent intelligence quotient in children born
preterm. Lancet 1992;339:261-4 (CD: 3) P-6: Bishop NJ, Dahlenburg SL, Fewtrell MS, Morley R,
Lucas A. Early diet of preterm infants and bone mineralization at
age five years. Acta Paediatr 1996;85:230-6 P-7: Carlson SE, Rhodes PG, Ferguson MG. Docosahexaenoic
acid status of preterm infants at birth and following feeding with
human milk or formula. Am J Clin Nutr 1986;44:798-804 P-8: Foreman-van Drongelen MMHP, van Houwelingen AC,
Kester ADM, Hasaart THM, Blanco CE, Hornstra G. Long-chain
polyunsaturated fatty acids in preterm infants: status at birth and
its influence on postnatal levels. J Pediatr 1997;126:611-8 P-9: Bier JB, Ferguson AE, Morales Y, Liebling JA, Oh
W, Vohr BR. Breastfeeding infants who were extremely low birth weight. Pediatrics
1997;100:p e3 P-10: Morley R, Cole TJ, Powell R, Lucas A. Mother's
choice to provide breastmilk and developmental outcome. Arch Dis Child 1988;63:1382-5 Childhood Cancer: CC-1: Schwartzbaum JA, George SL, Pratt CB, Davis B. An
exploratory study of environmental and medical factors potentially related
to childhood cancer. Med pediatr Oncol 1991;19:115-21 CC-2: Davis MK, Savitz DA. Graubard BI. Infant feeding
and childhood cancer. Lancet 1988;2:365-8 CC-3: Freudenheim JL, Marshall JR, Graham S, Laughlin
R, Vena JE, Bandera E, et al. Exposure to breastmilk in infancy and
the risk of breast cancer. Epidemiology 1994;5:324-31 CC-4: Shu XO, Linet MS, Steinbuch M, Wen WQ, Buckley
JD, Neglia JP, Potter JD et al. Breastfeeding and the risk of
childhood acute leukemia. J Nat Cancer Institute 1999;91:1765-72 CC-5: Davis MK. Review of the evidence for an
association between Infant feeding and childhood cancer. Int J Cancer 1998;Supplement
II:29-33 Gastrointestinal Disease and Infections: GI-1: Koletzko S, Sherman P, Corey M, Griffiths A,
Smith C. Role of infant feeding practices in the developement of Crohn’s
disease in childhood. Br Med J 1989;298:1617-8 GI-2: Greco L, Auricchio S, Mayer M, Grimaldi M. Case
control study on nutritional risk factors in celiac disease. J Pediatr
Gastroenterol Nutr 1988;7:395-8 GI-3: Duffy LC, Byers TE, Riepenhoff-Talty M, La Scolea
L, Zielezny M, Ogra PL. The effects of infant feeding on rotavirus-induced
gastroenteritis. A prospective study. Am J Pub Health 1986;76:259-63 GI-4: Hanson LA, Lindquist B, Hofvander Y, Zetterstrom
R. Breastfeeding as a protection against gastroenteritis and other
infections. Acta Pediatr Scand 1985;74:641-2 GI-5: Ruiz-Palacios GM, Calva JJ, Pickering LK,
Lopez-Vidal Y, Volkow P, Pezzarossi H, et al. Protection of
breastfed infants against Campylobacter diarrhea by antibodies in
human milk. J Pediatr 1990;116:707-13 GI-6: Cruz JR, Gil L, Cano F, Caceres P, Pareja G.
Breastmilk anti-Escherichia coli heat labile toxin IgA antibodies
protect against toxin-induced infantile diarrhea. Acta Pediatr Scand 1988;77:658-62 GI-7: Gillin FD, Reiner DS, Wang C-S. Human milk kills
parasitic intestinal protozoa. Science 1983;221:1290-2 GI-8: France GL, Marmer DJ, Steele RW. Breastfeeding
and Salmonella infection. Am J Dis Child 1980;134:147-52 GI-9: Haffejee IE. Cow’s milk-based formula, human
milk and soya feeds in acute infantile diarrhea: A therapeutic trial. J
Pediatr Gastroenterol Nutr 1990;10:193-8 GI-10: Lerman Y, Slepon R, Cohen D. Epidemiology of
acute diarrheal diseases in children in a high standard of living rural
settlement in Israel. Pediatr Infect Dis J. 1994;13:116-22 GI-11: Howie PW, Forsyth JS, Ogston SA, Clark A, Du V
Florey C. Protective effect of breastfeeding against infection. Br Med
J 1990;300:11-6 GI-12: Duffy LC, Riepenhoff-Talty M, Byers TE, La
Scolea LJ, Zielezny MA, Dryja DM et al. Modulation of rotavirum
enteritis during breastfeeding. Am J Dis Child 1986;140:1164-8 GI-13: Haddock RL, Cousens SN, Guzman CC. Infant diet
and salmonellosis. Am J Pub Health 1991;81:997-1000 GI-14: Scariati PD, Grummer-Strawn LM, Fein SB. A
longitudinal analysis of infant morbidity and the extent of breastfeeding
in the United States. Pediatrics 1997;99, June 1997;e5 (also for otitis
media) GI-15: Heacock HJ, Jeffery HE, BAker JL, Page M.
Influence of breast versus formula milk on physiological gastroesophageal
reflux In healthy, newborn Infants. J Pediatr Gastroenterol Nutr 1992:14:41-6 Urinary Tract Infection: UT-1: Pisacane A, Graziano L, Mazzarella G, Scarpellino
B, Zona G. Breastfeeding and urinary tract infection. J Pediatr 1992;120:87-9 Malocclusion: MA-1: Labbock MH, Hendershot GE. Does breastfeeding
protect against malocclusion? An analysis of the 1981 child health
supplement to the national health interview survey. Am J Prev Med 1987;3:227-32 MA-2: Palmer B. The influence of breastfeeding on the
development of the oral cavity: A commentary. J Hum Lact 1998;14:93-8 Formula as a heavy metal cocktail: HM-1: Koo WWK, Kaplan LA, Krug-Wispe SK. Aluminum
contamination of infant formulas. J Parenteral Enteral Nutrition 1988;12:170-3 HM-2: Davidsson L, Cederblad Å, Lönnerdal B,
Sandström B. Manganese absorption from human milk, cow’s milk and
infant formulas in humans. Am J Dis Child 1989;143:823-7 HM-3: Dabeka RW, McKenzie AD. Lead and cadmium levels
in commercial infant foods and dietary intake by infants 0-1 year old. Food
Additives and Contaminants 1988;5:333-42 Other Contamination due to bottle feeding: C-1: Mytjens HL, Roelofs-Willemse H, Jaspar GHJ.
Quality of powdered substitutes for breastmilk with regard to members of
the family Enterobacteriaceæ. J Clin Microbiol 1988;26:743-6 C-2: Biering G, Karlsson S, Clark NC, Jonsdottir KE,
Ludvigsson P, Steingrimsson O. Three cases of neonatal meningitis caused
by Enterobacter sakazakii in powdered milk. J Clin Microbiol 1989;27:2054-6 C-3: Westin JB. Ingestion of carcinogenic N-nitrosamines
by infants and children. Arch Environmental Health 1990;45:359-63 C-4: Schwarz KB, Cox JM, Sharma S, Clement L, Witter F,
Abbey H, et al. Prooxidant effects of maternal smoking and formula
In newborn Infants. J Pediatr Gastroenterol Nutr 1997;24:68-74 Allergy: A-1: Lucas A, Brooke OG, Morley R, Cole TJ, Bamford MF.
Early diet of preterm infants and development of allergic or atopic
disease: randomized prospective study. Br Med J 1990;300:837-40 A-2: Kajosaari M, Saarinen UM. Prophylaxis of atopic
disease by six months’ total solid food elimination. Acta Pediatr
Scand 1983;72:411-14 A-3: Ellis MH, Short JA, Heiner DC. Anaphylaxis after
ingestion of a recently introduced hydrolyzed whey protein protein
formula. J Pediatr 1991;118:74-7 A-4: Saarinen UM, Kajosaari M. Breastfeeding as
prophylaxis against atopic disease: prospective follow-up study until 17
years old. Lancet 1995;346:1065-69 A-5: Saylor JD, Bahna SL. Anaphylaxis to casein
hydrolysate formula. J Pediatr 1991;118:71-4 A-6: Marini A, Agosti M, Motta G, Mosca F. Effects of a
dietary and environmental prevention programme on the incidence of
allergic symptoms in high atopic risk infants: three years’ followup. Acta
Pædiatr 1996;Suppl 414 vol 85:1-19 A-7: Wright AL, Holberg CJ, Martinez FD, Halonen M,
Morgan W, Taussig LM. Epidemiology of physician diagnosed allergic
rhinitis In childhood. Pediatrics 1994:94:895-901 Miscellaneous: M-1: McJunkin JE, Bithoney WG, McCormick MC. Errors
in formula concentration in an outpatient population. J Pediatr 1987;111:848-50 M-1a: Abrams CAL, Phillips LL, Berkowitz C, Blacket PR,
Priebe CJ. Hazards of overconcentrated milk formula. JAMA 1975;232:1136-40 M-1b: Potur AH, Kalmaz N. An investigation into feeding
errors of 0-4 month old infants. J Trop Pediatr 1995;41:120-2 M-1c: Green HL, Moyer VA. Improper mixing of formula
due to reuse of hospital bottles. Arch Pediatr Adolesc Med 1995;149:97-9 M-1d: Coodin Fj, Gabrielson IW, Addiego JE. Formula
fatality. Pediatrics 1971;47:438-9 M-1e: Wilcox DT, Fiorello AB, Glick PL. Hypovolemic
shock and intestinal ischemia: a preventable complication of incomplete
formula labeling. J Pediatr 1993;122:103-4 M-2: Specker BL, Tsang RC, Ho ML, Landi TM, Gratton TL.
Low serum calcium and high parathyroid hormone levels in neonates
fed “humanized” cow’s milk-based formula. Am J Dis Child 1991;145:941-5 M2a: Jochum F, Fuchs A, Menzel H, Lombeck I. Selenium
in German infants fed breastmilk or different formulas. Acta Paediatr 1995;84:859-62 M-3: Kramer MS. Do breastfeeding and delayed
introduction of solid foods protect against subsequent obesity? J
Pediatr 1981;98:883-7 M-4: Dick G. The etiology of multiple sclerosis.
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